Search results for "Operative risk"

showing 7 items of 7 documents

Das Plattenepithelkarzinom des Ösophagus – Stellenwert der Chirurgie im therapeutischen Konzept

2010

Squamous cell carcinomas of the oesophagus are a completely different entity from adenocarcinomas in regard to their aetiopathology, tumour biology, co-morbidity, operative risk, and prognosis. For superficial squamous cell carcinomas, the risk of a relevant lymph node metastatisation already exists from the mucosal infiltration level m3 onward, and thus oncological resection is indicated. Neoadjuvant radiochemotherapy is the international standard for locally advanced squamous cell carcinoma. The early-response should be determined. Non-responders must be identified early, and a salvage operation with a justifiable operative risk should be carried out. Due to its high complete response rat…

medicine.medical_specialtyTumor biologybusiness.industryHistopathological responsemedicine.medical_treatmentGastroenterologyMultimodal therapymedicine.diseaseSurgerySurgical morbidityRadiation therapyClinical trialmedicine.anatomical_structureOncologyEsophagectomyCarcinomamedicineCombined Modality TherapyIn patientOperative riskbusinessLymph nodePathologicalNeoadjuvant therapyTumorDiagnostik & Therapie
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Does age over 80 years have to be a contraindication for lung cancer surgery—a nationwide database study

2018

IF 1.804 (2017); International audience; Background: Nowadays surgery remains the best treatment for localized lung cancer (LC). However, patients over 80 years old are often denied surgery because of the postoperative risk of death. This study aimed to estimate in-hospital mortality (IHM) and determine whether age over 80 is the most important predictor of IHM after LC surgery.Methods: From January 2005 to December 2015, 97,440 patients, including 4,438 patients over 80 years old, were operated on for LC and recorded in the French Administrative Database. Characteristics of patients, hospitals and surgery were analysed.Results: Crude IHM was 3.73% (n=3,639) and 7.77% (n=345) for the over 8…

Pulmonary and Respiratory Medicinemedicine.medical_specialtylobectomypredictive factors[SDV.CAN]Life Sciences [q-bio]/Cancer030230 surgery03 medical and health sciencesLiver disease0302 clinical medicinePostoperative riskmedicineLung cancerContraindicationLung cancer surgerybusiness.industryOver 80sNationwide databasein-hospital mortality (IHM)medicine.diseaseSublobar resection3. Good healthSurgeryOriginal ArticlePulmonary resectionbusinessnationwide database
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Surgical learning and guidance on operative risks and potential errors

2017

Purpose Within the framework of learning from errors, this study focused on how operative risks and potential errors are addressed in guidance to surgical residents during authentic surgical operations. The purpose of this paper is to improve patient safety and to diminish medical complications resulting from possible operating errors. Further in the process of the optimal contexts for instruction aimed at preventing risks and errors in the practical hospital environment was evaluated. Design/methodology/approach The five authentic surgical operations were analyzed, all of which were organized as training sessions for surgical residents. The data (collected via video-recoding) were analyze…

learning from errorsOrganizational Behavior and Human Resource ManagementoppimisympäristöKnowledge managementSocial PsychologyoppiminenProcess (engineering)Computer sciencemedia_common.quotation_subjectContext (language use)DevelopmentPatient safetyMeaningful learningOriginality0502 economics and businessharjoitteluOperations managementkirurgiamedia_commonTeamworkbusiness.industryLearning environment05 social sciencesopastus050301 educationLearning from errorsoperative risksvirheetbusiness0503 education050203 business & managementsurgical training
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Lessons Learned from the German Registry for Acute Aortic Dissection Type A (GERAADA) and Expectations for the Future

2014

The German Registry for Acute Aortic Dissection type A (GERAADA) is a prospective observational clinical multicenter registry that was launched in 2006. With more than 2,500 patients included from over 50 recruiting centers it is—to our knowledge—the most representative register for acute aortic dissection type A (AADA) currently available. We examined mortality and post-operative events as well as the influence of various pre- and intraoperative factors on these endpoints. Among patients registered, 30-day mortality is 15.9 %. 13.4 % of patients experienced postoperatively a new neurological deficit and a total of 10.5 % of patients suffered from permanent neurological impairment 30 days a…

Aortic dissectionmedicine.medical_specialtybusiness.industryGeneral surgeryPreoperative riskmedicine.diseaseAortic arch surgerylanguage.human_languageSurgeryGermanlanguageMedicineObservational studySources of errorbusinessNeurological impairmentNeurological deficit
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Preoperative risk factors for postoperative delirium (POD) after urological surgery in the elderly

2011

The aim of this observational study was to investigate the occurrence of postoperative delirium (POD) in elderly patients undergoing urological surgery and to identify those factors associated with delirium. Ninety consecutive patients (81 males and 9 females; average age of 74.3 ± 0.40 years), undergoing urological surgery in University-Hospital Urological Clinic were selected. Personal, medical, cognitive and functional data, biochemical parameters, preoperative medications, conduct of surgery and anesthesia and details of hemodynamic control were collected as predictors of delirium. After surgery, the subjects were divided on the basis of delirium onset within a week observation period. …

Malemedicine.medical_specialtyAgingHealth (social science)Activities of daily livingPreoperative riskHemodynamicsbehavioral disciplines and activitiesCohort StudiesPostoperative ComplicationsCognitionRisk FactorsInternal medicinemental disordersActivities of Daily LivingHumansMedicinePostoperative deliriumGeriatric AssessmentAgedDelirium; Hypotension; Multidimensional assessment; Older people; Urological surgerybusiness.industryRisk FactorUrological surgeryDeliriumUrological surgerynervous system diseasesAnesthesiaDeliriumUrologic Surgical ProceduresObservational studyFemalePostoperative ComplicationGeriatrics and Gerontologymedicine.symptomHypotensionOlder peopleCohort StudiebusinessGerontologyClock drawing testMultidimensional assessmentHuman
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EPCT-15. RAPID EPIGENOMIC CLASSIFICATION OF BRAIN TUMORS ENABLES INTRAOPERATIVE NEUROSURGICAL RISK MODULATION

2021

Abstract Background Clear identification of tumor subtype is the main predictor of patient outcome and ultimately what is considered an adequate level of surgical risk. At brain tumor resection, imaging modalities and intraoperative histology often give an ambigious diagnosis, complicating intraoperative surgical decision-making. Here, we report a nanopore DNA methylation analysis (NDMA) sequencing approach combined with machine learning for classification of tumor entities that could be used intraoperatively. Methods We analyzed 50 biopsies obtained from biobanked tissue (43, prospective) or sampled at surgery (7, intraoperative) from 20 female and 30 male patients with a median age of 8 y…

Cancer Researchmedicine.medical_specialtyIntra operativebusiness.industryTranslational/Early Phase Clinical TrialsTumor excisionOncologymedicineAcademicSubjects/MED00300AcademicSubjects/MED00310Neurology (clinical)RadiologyOperative riskbusinessEpigenomicsNeuro-Oncology
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Mitral Valve Repair Without Using Rings or Slings

1989

Reconstructive surgery of the mitral valve is still deemed superior to prosthetic replacement because of the lower operative risk as well as the fewer thromboembolic complications [1, 2]. Whereas closed or open commissurotomy of a stenosed mitral valve has been routine in the past and present [3], reconstructive measures for incompetent valves have been among those least often performed. The use of rigid or semi-flexible annular rings [4–9] has significantly contributed to progress in this field. However, these are not suitable for repair of all valvular lesions and undoubtedly have at least some of the negative features of prosthetic substitutes. We have therefore started a program of mitr…

medicine.medical_specialtyAnterior leafletReconstructive surgeryBeating heartMitral valve repairbusiness.industrymedicine.medical_treatmentAnnular ringsSurgerymedicine.anatomical_structureMitral valvecardiovascular systemmedicineOperative riskCommissurotomybusiness
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